Stable Angiogenesis: Mechanically Defined Microenvironment Promotes Stabilization of Microvasculature, Which Correlates with the Enrichment of a Novel Piezo‐1+ Population of Circulating CD11b+/CD115+ Monocytes (Adv. Mater. 21/2019)

In article number 1808050, V. Prasad Shastri and co‐workers describe the formation of a new perfused blood vessel. The stabilization of this neovessel by a mechanically defined hydrogel microenvironment through the recruitment (extravasation) of mechanosensing CD11b+/piezo‐1+ cells by this microenvi...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2019-05, Vol.31 (21), p.n/a
Main Authors: Forget, Aurelien, Gianni‐Barrera, Roberto, Uccelli, Andrea, Sarem, Melika, Kohler, Esther, Fogli, Barbara, Muraro, Manuele G., Bichet, Sandrine, Aumann, Konrad, Banfi, Andrea, Shastri, V. Prasad
Format: Article
Language:English
Subjects:
Blood vessels
carboxylated agarose
Hydrogels
Materials science
mechanobiology
Muscles
Piezo‐1
Stabilization
therapeutic angiogenesis
vessel stabilization
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Summary:In article number 1808050, V. Prasad Shastri and co‐workers describe the formation of a new perfused blood vessel. The stabilization of this neovessel by a mechanically defined hydrogel microenvironment through the recruitment (extravasation) of mechanosensing CD11b+/piezo‐1+ cells by this microenvironment is depicted against the backdrop of a hematoxylin‐eosinstained image of a skeletal muscle.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201970150