Inspirations from nature. New reactions, new therapeutic leads, and new drug delivery systems

Studies in our laboratory focus on problems in chemistry (new reactions and synthesis), biology (novel modes of action), and medicine (new therapeutic leads and drug delivery systems). These interconnected and often synergistic activities are inspired by an interest in novel structures, frequently f...

Full description

Saved in:
Bibliographic Details
Published in:Pure and applied chemistry 2003-01, Vol.75 (2), p.143-155
Main Authors: Wender, P. A., Baryza, J. L., Brenner, S. E., Clarke, M. O., Gamber, Gabriel G., Horan, J. C., Jessop, T. C., Kan, Cindy, Pattabiraman, K., Williams, T. J.
Format: Article
Language:English
Subjects:
Chemical reactions
Chemical synthesis
Drug delivery systems
Laboratories
Medical research
Organic chemistry
Transdermal medication
Transition metals
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c2113-26d53bcd1519d79e9af18a2540861b2a8dd30da493a77917c1c97ad4e083610c3
cites cdi_FETCH-LOGICAL-c2113-26d53bcd1519d79e9af18a2540861b2a8dd30da493a77917c1c97ad4e083610c3
container_end_page 155
container_issue 2
container_start_page 143
container_title Pure and applied chemistry
container_volume 75
creator Wender, P. A.
Baryza, J. L.
Brenner, S. E.
Clarke, M. O.
Gamber, Gabriel G.
Horan, J. C.
Jessop, T. C.
Kan, Cindy
Pattabiraman, K.
Williams, T. J.
description Studies in our laboratory focus on problems in chemistry (new reactions and synthesis), biology (novel modes of action), and medicine (new therapeutic leads and drug delivery systems). These interconnected and often synergistic activities are inspired by an interest in novel structures, frequently from nature, that possess unique modes of action and significant clinical potential. Described herein are some examples of recent work from our laboratory that have led to new transition metal-catalyzed reactions, a new and remarkably potent therapeutic lead, and new drug delivery systems that are in clinical trials.
doi_str_mv 10.1351/pac200375020143
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2230183409</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2230183409</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2113-26d53bcd1519d79e9af18a2540861b2a8dd30da493a77917c1c97ad4e083610c3</originalsourceid><addsrcrecordid>eNp1UMtLwzAYD6LgnJ69BrzaLV8eTXMSGb5g6EWPUr4l6ezY2pq0jv73dpsgCJ6-x-8FP0IugU1AKJg2aDljQivGGUhxREYgUpUIptUxGQ2ISKSS6pScxbhijEkj-Yi8P1WxKQO2ZV1FWoR6Qytsu-An9NlvafBo99A1rYaz_fABG9-1paVrj254Y-X2kAvdkjq_Lr986GnsY-s38ZycFLiO_uJnjsnb_d3r7DGZvzw8zW7nieUAIuGpU2JhHSgwThtvsIAMuZIsS2HBMXNOMIfSCNTagLZgjUYnPctECsyKMbk6-Dah_ux8bPNV3YVqiMw5FwwyIZkZWNMDy4Y6xuCLvAnlBkOfA8t3HeZ_OhwUNwfFFtetD84vQ9cPy6_9P0qteC52Dt-SBngV</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2230183409</pqid></control><display><type>article</type><title>Inspirations from nature. New reactions, new therapeutic leads, and new drug delivery systems</title><source>Free Full-Text Journals in Chemistry</source><creator>Wender, P. A. ; Baryza, J. L. ; Brenner, S. E. ; Clarke, M. O. ; Gamber, Gabriel G. ; Horan, J. C. ; Jessop, T. C. ; Kan, Cindy ; Pattabiraman, K. ; Williams, T. J.</creator><creatorcontrib>Wender, P. A. ; Baryza, J. L. ; Brenner, S. E. ; Clarke, M. O. ; Gamber, Gabriel G. ; Horan, J. C. ; Jessop, T. C. ; Kan, Cindy ; Pattabiraman, K. ; Williams, T. J.</creatorcontrib><description>Studies in our laboratory focus on problems in chemistry (new reactions and synthesis), biology (novel modes of action), and medicine (new therapeutic leads and drug delivery systems). These interconnected and often synergistic activities are inspired by an interest in novel structures, frequently from nature, that possess unique modes of action and significant clinical potential. Described herein are some examples of recent work from our laboratory that have led to new transition metal-catalyzed reactions, a new and remarkably potent therapeutic lead, and new drug delivery systems that are in clinical trials.</description><identifier>ISSN: 0033-4545</identifier><identifier>EISSN: 1365-3075</identifier><identifier>DOI: 10.1351/pac200375020143</identifier><language>eng</language><publisher>Berlin: De Gruyter</publisher><subject>Chemical reactions ; Chemical synthesis ; Drug delivery systems ; Laboratories ; Medical research ; Organic chemistry ; Transdermal medication ; Transition metals</subject><ispartof>Pure and applied chemistry, 2003-01, Vol.75 (2), p.143-155</ispartof><rights>2013 Walter de Gruyter GmbH, Berlin/Boston</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2113-26d53bcd1519d79e9af18a2540861b2a8dd30da493a77917c1c97ad4e083610c3</citedby><cites>FETCH-LOGICAL-c2113-26d53bcd1519d79e9af18a2540861b2a8dd30da493a77917c1c97ad4e083610c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Wender, P. A.</creatorcontrib><creatorcontrib>Baryza, J. L.</creatorcontrib><creatorcontrib>Brenner, S. E.</creatorcontrib><creatorcontrib>Clarke, M. O.</creatorcontrib><creatorcontrib>Gamber, Gabriel G.</creatorcontrib><creatorcontrib>Horan, J. C.</creatorcontrib><creatorcontrib>Jessop, T. C.</creatorcontrib><creatorcontrib>Kan, Cindy</creatorcontrib><creatorcontrib>Pattabiraman, K.</creatorcontrib><creatorcontrib>Williams, T. J.</creatorcontrib><title>Inspirations from nature. New reactions, new therapeutic leads, and new drug delivery systems</title><title>Pure and applied chemistry</title><description>Studies in our laboratory focus on problems in chemistry (new reactions and synthesis), biology (novel modes of action), and medicine (new therapeutic leads and drug delivery systems). These interconnected and often synergistic activities are inspired by an interest in novel structures, frequently from nature, that possess unique modes of action and significant clinical potential. Described herein are some examples of recent work from our laboratory that have led to new transition metal-catalyzed reactions, a new and remarkably potent therapeutic lead, and new drug delivery systems that are in clinical trials.</description><subject>Chemical reactions</subject><subject>Chemical synthesis</subject><subject>Drug delivery systems</subject><subject>Laboratories</subject><subject>Medical research</subject><subject>Organic chemistry</subject><subject>Transdermal medication</subject><subject>Transition metals</subject><issn>0033-4545</issn><issn>1365-3075</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><recordid>eNp1UMtLwzAYD6LgnJ69BrzaLV8eTXMSGb5g6EWPUr4l6ezY2pq0jv73dpsgCJ6-x-8FP0IugU1AKJg2aDljQivGGUhxREYgUpUIptUxGQ2ISKSS6pScxbhijEkj-Yi8P1WxKQO2ZV1FWoR6Qytsu-An9NlvafBo99A1rYaz_fABG9-1paVrj254Y-X2kAvdkjq_Lr986GnsY-s38ZycFLiO_uJnjsnb_d3r7DGZvzw8zW7nieUAIuGpU2JhHSgwThtvsIAMuZIsS2HBMXNOMIfSCNTagLZgjUYnPctECsyKMbk6-Dah_ux8bPNV3YVqiMw5FwwyIZkZWNMDy4Y6xuCLvAnlBkOfA8t3HeZ_OhwUNwfFFtetD84vQ9cPy6_9P0qteC52Dt-SBngV</recordid><startdate>20030101</startdate><enddate>20030101</enddate><creator>Wender, P. A.</creator><creator>Baryza, J. L.</creator><creator>Brenner, S. E.</creator><creator>Clarke, M. O.</creator><creator>Gamber, Gabriel G.</creator><creator>Horan, J. C.</creator><creator>Jessop, T. C.</creator><creator>Kan, Cindy</creator><creator>Pattabiraman, K.</creator><creator>Williams, T. J.</creator><general>De Gruyter</general><general>Walter de Gruyter GmbH</general><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope></search><sort><creationdate>20030101</creationdate><title>Inspirations from nature. New reactions, new therapeutic leads, and new drug delivery systems</title><author>Wender, P. A. ; Baryza, J. L. ; Brenner, S. E. ; Clarke, M. O. ; Gamber, Gabriel G. ; Horan, J. C. ; Jessop, T. C. ; Kan, Cindy ; Pattabiraman, K. ; Williams, T. J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2113-26d53bcd1519d79e9af18a2540861b2a8dd30da493a77917c1c97ad4e083610c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Chemical reactions</topic><topic>Chemical synthesis</topic><topic>Drug delivery systems</topic><topic>Laboratories</topic><topic>Medical research</topic><topic>Organic chemistry</topic><topic>Transdermal medication</topic><topic>Transition metals</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wender, P. A.</creatorcontrib><creatorcontrib>Baryza, J. L.</creatorcontrib><creatorcontrib>Brenner, S. E.</creatorcontrib><creatorcontrib>Clarke, M. O.</creatorcontrib><creatorcontrib>Gamber, Gabriel G.</creatorcontrib><creatorcontrib>Horan, J. C.</creatorcontrib><creatorcontrib>Jessop, T. C.</creatorcontrib><creatorcontrib>Kan, Cindy</creatorcontrib><creatorcontrib>Pattabiraman, K.</creatorcontrib><creatorcontrib>Williams, T. J.</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><jtitle>Pure and applied chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wender, P. A.</au><au>Baryza, J. L.</au><au>Brenner, S. E.</au><au>Clarke, M. O.</au><au>Gamber, Gabriel G.</au><au>Horan, J. C.</au><au>Jessop, T. C.</au><au>Kan, Cindy</au><au>Pattabiraman, K.</au><au>Williams, T. J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inspirations from nature. New reactions, new therapeutic leads, and new drug delivery systems</atitle><jtitle>Pure and applied chemistry</jtitle><date>2003-01-01</date><risdate>2003</risdate><volume>75</volume><issue>2</issue><spage>143</spage><epage>155</epage><pages>143-155</pages><issn>0033-4545</issn><eissn>1365-3075</eissn><abstract>Studies in our laboratory focus on problems in chemistry (new reactions and synthesis), biology (novel modes of action), and medicine (new therapeutic leads and drug delivery systems). These interconnected and often synergistic activities are inspired by an interest in novel structures, frequently from nature, that possess unique modes of action and significant clinical potential. Described herein are some examples of recent work from our laboratory that have led to new transition metal-catalyzed reactions, a new and remarkably potent therapeutic lead, and new drug delivery systems that are in clinical trials.</abstract><cop>Berlin</cop><pub>De Gruyter</pub><doi>10.1351/pac200375020143</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0033-4545
ispartof Pure and applied chemistry, 2003-01, Vol.75 (2), p.143-155
issn 0033-4545
1365-3075
language eng
recordid cdi_proquest_journals_2230183409
source Free Full-Text Journals in Chemistry
subjects Chemical reactions
Chemical synthesis
Drug delivery systems
Laboratories
Medical research
Organic chemistry
Transdermal medication
Transition metals
title Inspirations from nature. New reactions, new therapeutic leads, and new drug delivery systems
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T19%3A58%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Inspirations%20from%20nature.%20New%20reactions,%20new%20therapeutic%20leads,%20and%20new%20drug%20delivery%20systems&rft.jtitle=Pure%20and%20applied%20chemistry&rft.au=Wender,%20P.%20A.&rft.date=2003-01-01&rft.volume=75&rft.issue=2&rft.spage=143&rft.epage=155&rft.pages=143-155&rft.issn=0033-4545&rft.eissn=1365-3075&rft_id=info:doi/10.1351/pac200375020143&rft_dat=%3Cproquest_cross%3E2230183409%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c2113-26d53bcd1519d79e9af18a2540861b2a8dd30da493a77917c1c97ad4e083610c3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2230183409&rft_id=info:pmid/&rfr_iscdi=true