Predicting Success: Patterns of Cortical Activation and Deactivation Prior to Response Inhibition

The present study investigated the relationships between attention and other preparatory processes prior to a response inhibition task and the processes involved in the inhibition itself. To achieve this, a mixed fMRI design was employed to identify the functional areas activated during both inhibit...

Full description

Saved in:
Bibliographic Details
Published in:Journal of cognitive neuroscience 2004-06, Vol.16 (5), p.776-785
Main Authors: Hester, Robert L., Murphy, Kevin, Foxe, John J., Foxe, Deirdre M., Javitt, Daniel C., Garavan, Hugh
Format: Article
Language:English
Subjects:
Adult
Anatomical correlates of behavior
Attention - physiology
Behavioral psychophysiology
Biological and medical sciences
Brain
Brain Mapping
Cerebral Cortex - anatomy & histology
Cerebral Cortex - physiology
Cognition & reasoning
Cues
Evoked Potentials - physiology
Female
Functional Laterality
Fundamental and applied biological sciences. Psychology
Humans
Image Processing, Computer-Assisted
Inhibition (Psychology)
Magnetic Resonance Imaging
Male
Mental Processes - physiology
Neurology
NMR
Nuclear magnetic resonance
Pattern Recognition, Visual - physiology
Photic Stimulation - methods
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Studies
Time Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The present study investigated the relationships between attention and other preparatory processes prior to a response inhibition task and the processes involved in the inhibition itself. To achieve this, a mixed fMRI design was employed to identify the functional areas activated during both inhibition decision events and the block of trials following a visual cue introduced 2 to 7 sec prior (cue period). Preparing for successful performance produced increases in activation for both the cue period and the inhibition itself in the frontoparietal cortical network. Furthermore, preparation produced activation decreases in midline areas (insula and medial prefrontal) argued to be responsible for monitoring internal emotional states, and these cue period deactivations alone predicted subsequent success or failure. The results suggest that when cues are provided to signify the imminent requirement for behavioral control, successful performance results from a coordinated pattern of preparatory activation in task-relevant areas and deactivation of task-irrelevant ones.
ISSN:0898-929X
1530-8898
DOI:10.1162/089892904970726