Population Estimates of Extended Family Structure and Size

Background: Population-based estimates of biological family size can be useful for planning genetic studies, assessing how distributions of relatives affect disease associations with family history and estimating prevalence of potential family support. Methods: Mean family size per person is estimat...

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Bibliographic Details
Published in:Community genetics 2008-01, Vol.11 (6), p.331-342
Main Authors: Garceau, Anne, Wideroff, Louise, McNeel, Timothy, Dunn, Marsha, Graubard, Barry I.
Format: Article
Language:English
Subjects:
Family size
Genetics
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Summary:Background: Population-based estimates of biological family size can be useful for planning genetic studies, assessing how distributions of relatives affect disease associations with family history and estimating prevalence of potential family support. Methods: Mean family size per person is estimated from a population-based telephone survey (n = 1,019). Results: After multivariate adjustment for demographic variables, older and non-White respondents reported greater mean numbers of total, first- and second-degree relatives. Females reported more total and first-degree relatives, while less educated respondents reported more second-degree relatives. Conclusions: Demographic differences in family size have implications for genetic research. Therefore, periodic collection of family structure data in representative populations would be useful.
ISSN:1422-2795
1662-4246
1422-2833
1662-8063
DOI:10.1159/000133305