Purple glove syndrome following intravenous phenytoin administration

Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb. Several risk factors have been associated with the development of PGS; however, the etiology remains unkn...

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Bibliographic Details
Published in:Vascular medicine (London, England) England), 2007-02, Vol.12 (1), p.29-31
Main Authors: Chokshi, Reena, Openshaw, John, Mehta, Nehal N, Mohler, Emile
Format: Article
Language:English
Subjects:
Aged
Alcoholism and acute alcohol poisoning
Anticonvulsants - administration & dosage
Anticonvulsants - adverse effects
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Cyanosis - chemically induced
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Edema - chemically induced
Epilepsy, Tonic-Clonic - drug therapy
Hand
Humans
Infusions, Intravenous
Injuries of the limb. Injuries of the spine
Male
Medical sciences
Pain - chemically induced
Phenytoin - administration & dosage
Phenytoin - adverse effects
Syndrome
Toxicology
Traumas. Diseases due to physical agents
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Description
Summary:Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb. Several risk factors have been associated with the development of PGS; however, the etiology remains unknown. We present a case of PGS and briefly review the current understanding of this syndrome.
ISSN:1358-863X
1477-0377
DOI:10.1177/1358863X07076551