Polysiloxane based on hydroxyl-containing monomer. Preparation, properties and biomedical application

A method for synthesis of hyperbranched polysiloxane based on N -methyl- N -(2,3,4,5,6-pentahydroxyhexyl)- N ’-(3-triethoxysilylpropyl)urea is proposed. In water, the polymer forms nanoparticles capable of holding low soluble luminophores (tetracyanotetraarylporphyrazines) due to non-covalent intera...

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Bibliographic Details
Published in:Russian chemical bulletin 2019-05, Vol.68 (5), p.1075-1080
Main Authors: Lyubova, T. S., Zakharycheva, N. S., Zakharychev, E. A., Lermontova, S. A., Ladilina, E. Yu, Klapshina, L. G.
Format: Article
Language:English
Subjects:
Biocompatibility
Biomedical materials
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
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Inorganic Chemistry
Medical imaging
Nanoparticles
Organic Chemistry
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Summary:A method for synthesis of hyperbranched polysiloxane based on N -methyl- N -(2,3,4,5,6-pentahydroxyhexyl)- N ’-(3-triethoxysilylpropyl)urea is proposed. In water, the polymer forms nanoparticles capable of holding low soluble luminophores (tetracyanotetraarylporphyrazines) due to non-covalent interaction. Intensively luminescent stable aqueous suspensions based on non-toxic siloxane nanoparticles can be used in bioimaging.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-019-2522-3