Fluorescent Labeling of Oligonucleotide Probes for Double Indicator Microarray Hybridization Analysis

Herein, we present a synthesis of a molecular construct based on the polysulfonated indocarbocyanine dye and the lysine. The chemical structure of the construct obtained enables fluorescent labeling of oligonucleotide probes designed for the immobilization on the oligonucleotide biochips.

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Bibliographic Details
Published in:Russian journal of bioorganic chemistry 2019-05, Vol.45 (3), p.217-220
Main Authors: Shershov, V. E., Miftakhov, R. A., Kuznetsova, V. E., Timofeev, E. N., Grechishnikova, I. V., Spitsyn, M. A., Guseinov, T. O., Lapa, S. A., Zasedatelev, A. S., Chudinov, A. V.
Format: Article
Language:English
Subjects:
Biochemistry
Biochips
Biomedical and Life Sciences
Biomedicine
Bioorganic Chemistry
Chemical synthesis
Fluorescence
Labeling
Letter to Editor
Life Sciences
Lysine
Organic Chemistry
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Description
Summary:Herein, we present a synthesis of a molecular construct based on the polysulfonated indocarbocyanine dye and the lysine. The chemical structure of the construct obtained enables fluorescent labeling of oligonucleotide probes designed for the immobilization on the oligonucleotide biochips.
ISSN:1068-1620
1608-330X
DOI:10.1134/S1068162019030051