Synthesis and Antimicrobial Activity of 3-{2-[(1-Aryl-1H-1,2,3-triazol-4-yl)methoxy]-5-fluorophenyl}isoxazoles

A novel series 3-{2-[(1-aryl-1 H -1,2,3-triazol-4-yl)methoxy]-5-fluorophenyl}isoxazoles derivatives is synthesized from 1-(5-fluoro-2-hydroxyphenyl)ethanone. All the synthesized compounds are characterized by IR, 1 H and 13 C NMR, and mass spectral data, and tested for their in vitro antimicrobial a...

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Bibliographic Details
Published in:Russian journal of general chemistry 2019-06, Vol.89 (6), p.1221-1224
Main Authors: Kumar, K. Santhosh, Mohanty, S., Reddy, G. P., Siddaiah, V., Lilakar, J. D., Goud, G. L.
Format: Article
Language:English
Subjects:
Antifungal agents
Antiinfectives and antibacterials
Antimicrobial agents
Aromatic compounds
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
NMR
Nuclear magnetic resonance
Synthesis
Triazoles
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Summary:A novel series 3-{2-[(1-aryl-1 H -1,2,3-triazol-4-yl)methoxy]-5-fluorophenyl}isoxazoles derivatives is synthesized from 1-(5-fluoro-2-hydroxyphenyl)ethanone. All the synthesized compounds are characterized by IR, 1 H and 13 C NMR, and mass spectral data, and tested for their in vitro antimicrobial activity against bacterial and fungal organisms.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363219060197