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Re-irradiation for humeral epicondylitis
BackgroundHumeral epicondylitis is a common elbow disease. The prevalence is about 1.7%. One of the most effective treatment options is radiotherapy. Some authors mention that they apply a second or third course of radiation for recurrent pain or partial or no response to the initial course. As the...
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Published in: | Strahlentherapie und Onkologie 2020-03, Vol.196 (3), p.262-269 |
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description | BackgroundHumeral epicondylitis is a common elbow disease. The prevalence is about 1.7%. One of the most effective treatment options is radiotherapy. Some authors mention that they apply a second or third course of radiation for recurrent pain or partial or no response to the initial course. As the results of a re-irradiation have not been systematically analyzed, the aim of this study was to document the results of repeated radiation treatment and to identify those patients who will benefit.Material and methodsThe analysis was performed on patients from three German radiotherapy institutions and included 99 re-irradiated elbows. Pain was documented with the numeric rating scale (NRS). Evaluation of the NRS was done before and directly after each radiation therapy as well as for the follow-up of 24 months. The median age of the patients was 51 years with 48.8% male and 51.2% female patients. Repeated radiation was indicated because the initial radiotherapy resulted in 39.7% of no response, in 41.0% of partial response and in 19.3% of recurrent pain.ResultsA significant response to re-irradiation was found. For the whole sample the median pain score was 6 before re-irradiation, 3 after 6 weeks, 2 after 12 months and 1 after 24 months. The percentage of patients being free of pain or with very little pain was 50.9% 24 months after re-irradiation. All subgroups, notably those with no response, partial response and recurrent pain had a significant reduction of pain.ConclusionRe-irradiation of humeral epicondylitis is an effective and safe treatment. All subgroups showed a good response to re-irradiation for at least 24 months. |
doi_str_mv | 10.1007/s00066-019-01493-y |
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The prevalence is about 1.7%. One of the most effective treatment options is radiotherapy. Some authors mention that they apply a second or third course of radiation for recurrent pain or partial or no response to the initial course. As the results of a re-irradiation have not been systematically analyzed, the aim of this study was to document the results of repeated radiation treatment and to identify those patients who will benefit.Material and methodsThe analysis was performed on patients from three German radiotherapy institutions and included 99 re-irradiated elbows. Pain was documented with the numeric rating scale (NRS). Evaluation of the NRS was done before and directly after each radiation therapy as well as for the follow-up of 24 months. The median age of the patients was 51 years with 48.8% male and 51.2% female patients. Repeated radiation was indicated because the initial radiotherapy resulted in 39.7% of no response, in 41.0% of partial response and in 19.3% of recurrent pain.ResultsA significant response to re-irradiation was found. For the whole sample the median pain score was 6 before re-irradiation, 3 after 6 weeks, 2 after 12 months and 1 after 24 months. The percentage of patients being free of pain or with very little pain was 50.9% 24 months after re-irradiation. All subgroups, notably those with no response, partial response and recurrent pain had a significant reduction of pain.ConclusionRe-irradiation of humeral epicondylitis is an effective and safe treatment. All subgroups showed a good response to re-irradiation for at least 24 months.</description><identifier>ISSN: 0179-7158</identifier><identifier>EISSN: 1439-099X</identifier><identifier>DOI: 10.1007/s00066-019-01493-y</identifier><language>eng</language><publisher>Heidelberg: Springer Nature B.V</publisher><subject>Identification methods ; Irradiation ; Pain ; Radiation therapy ; Subgroups</subject><ispartof>Strahlentherapie und Onkologie, 2020-03, Vol.196 (3), p.262-269</ispartof><rights>Strahlentherapie und Onkologie is a copyright of Springer, (2019). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c770-a7e608e92244ad65205b9c7b44911e402f0ccf7e8b01dc4ccc7a2ac5cef5831c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Hautmann, Matthias G</creatorcontrib><creatorcontrib>Beyer, Lukas P</creatorcontrib><creatorcontrib>Hipp Matthias</creatorcontrib><creatorcontrib>Neumaier, Ulrich</creatorcontrib><creatorcontrib>Steger, Felix</creatorcontrib><creatorcontrib>Dietl, Barbara</creatorcontrib><creatorcontrib>Evert Katja</creatorcontrib><creatorcontrib>Kölbl Oliver Prof</creatorcontrib><creatorcontrib>Süß Christoph</creatorcontrib><title>Re-irradiation for humeral epicondylitis</title><title>Strahlentherapie und Onkologie</title><description>BackgroundHumeral epicondylitis is a common elbow disease. The prevalence is about 1.7%. One of the most effective treatment options is radiotherapy. Some authors mention that they apply a second or third course of radiation for recurrent pain or partial or no response to the initial course. As the results of a re-irradiation have not been systematically analyzed, the aim of this study was to document the results of repeated radiation treatment and to identify those patients who will benefit.Material and methodsThe analysis was performed on patients from three German radiotherapy institutions and included 99 re-irradiated elbows. Pain was documented with the numeric rating scale (NRS). Evaluation of the NRS was done before and directly after each radiation therapy as well as for the follow-up of 24 months. The median age of the patients was 51 years with 48.8% male and 51.2% female patients. Repeated radiation was indicated because the initial radiotherapy resulted in 39.7% of no response, in 41.0% of partial response and in 19.3% of recurrent pain.ResultsA significant response to re-irradiation was found. For the whole sample the median pain score was 6 before re-irradiation, 3 after 6 weeks, 2 after 12 months and 1 after 24 months. The percentage of patients being free of pain or with very little pain was 50.9% 24 months after re-irradiation. All subgroups, notably those with no response, partial response and recurrent pain had a significant reduction of pain.ConclusionRe-irradiation of humeral epicondylitis is an effective and safe treatment. All subgroups showed a good response to re-irradiation for at least 24 months.</description><subject>Identification methods</subject><subject>Irradiation</subject><subject>Pain</subject><subject>Radiation therapy</subject><subject>Subgroups</subject><issn>0179-7158</issn><issn>1439-099X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNotjcFKxDAURYMoWEd_wFXBjZvoe2mS1yxl0FEYEGQW7ob0NcUMtR2TdjF_b0EXl8PZnCvELcIDAtBjBgBrJaBbpl0lT2eiQF0t6tznuSgAyUlCU1-Kq5wPAGi104W4_wgypuTb6Kc4DmU3pvJr_g7J92U4Rh6H9tTHKeZrcdH5Poebf67E7uV5t36V2_fN2_ppK5kIpKdgoQ5OKa19a40C0zimRmuHGDSoDpg7CnUD2LJmZvLKs-HQmbpCrlbi7i97TOPPHPK0P4xzGpbHvVKGnCVjoPoFxDxDig</recordid><startdate>20200301</startdate><enddate>20200301</enddate><creator>Hautmann, Matthias G</creator><creator>Beyer, Lukas P</creator><creator>Hipp Matthias</creator><creator>Neumaier, Ulrich</creator><creator>Steger, Felix</creator><creator>Dietl, Barbara</creator><creator>Evert Katja</creator><creator>Kölbl Oliver Prof</creator><creator>Süß Christoph</creator><general>Springer Nature B.V</general><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20200301</creationdate><title>Re-irradiation for humeral epicondylitis</title><author>Hautmann, Matthias G ; Beyer, Lukas P ; Hipp Matthias ; Neumaier, Ulrich ; Steger, Felix ; Dietl, Barbara ; Evert Katja ; Kölbl Oliver Prof ; Süß Christoph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c770-a7e608e92244ad65205b9c7b44911e402f0ccf7e8b01dc4ccc7a2ac5cef5831c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Identification methods</topic><topic>Irradiation</topic><topic>Pain</topic><topic>Radiation therapy</topic><topic>Subgroups</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hautmann, Matthias G</creatorcontrib><creatorcontrib>Beyer, Lukas P</creatorcontrib><creatorcontrib>Hipp Matthias</creatorcontrib><creatorcontrib>Neumaier, Ulrich</creatorcontrib><creatorcontrib>Steger, Felix</creatorcontrib><creatorcontrib>Dietl, Barbara</creatorcontrib><creatorcontrib>Evert Katja</creatorcontrib><creatorcontrib>Kölbl Oliver Prof</creatorcontrib><creatorcontrib>Süß Christoph</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest advanced technologies & aerospace journals</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Strahlentherapie und Onkologie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hautmann, Matthias G</au><au>Beyer, Lukas P</au><au>Hipp Matthias</au><au>Neumaier, Ulrich</au><au>Steger, Felix</au><au>Dietl, Barbara</au><au>Evert Katja</au><au>Kölbl Oliver Prof</au><au>Süß Christoph</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Re-irradiation for humeral epicondylitis</atitle><jtitle>Strahlentherapie und Onkologie</jtitle><date>2020-03-01</date><risdate>2020</risdate><volume>196</volume><issue>3</issue><spage>262</spage><epage>269</epage><pages>262-269</pages><issn>0179-7158</issn><eissn>1439-099X</eissn><abstract>BackgroundHumeral epicondylitis is a common elbow disease. The prevalence is about 1.7%. One of the most effective treatment options is radiotherapy. Some authors mention that they apply a second or third course of radiation for recurrent pain or partial or no response to the initial course. As the results of a re-irradiation have not been systematically analyzed, the aim of this study was to document the results of repeated radiation treatment and to identify those patients who will benefit.Material and methodsThe analysis was performed on patients from three German radiotherapy institutions and included 99 re-irradiated elbows. Pain was documented with the numeric rating scale (NRS). Evaluation of the NRS was done before and directly after each radiation therapy as well as for the follow-up of 24 months. The median age of the patients was 51 years with 48.8% male and 51.2% female patients. Repeated radiation was indicated because the initial radiotherapy resulted in 39.7% of no response, in 41.0% of partial response and in 19.3% of recurrent pain.ResultsA significant response to re-irradiation was found. For the whole sample the median pain score was 6 before re-irradiation, 3 after 6 weeks, 2 after 12 months and 1 after 24 months. The percentage of patients being free of pain or with very little pain was 50.9% 24 months after re-irradiation. All subgroups, notably those with no response, partial response and recurrent pain had a significant reduction of pain.ConclusionRe-irradiation of humeral epicondylitis is an effective and safe treatment. All subgroups showed a good response to re-irradiation for at least 24 months.</abstract><cop>Heidelberg</cop><pub>Springer Nature B.V</pub><doi>10.1007/s00066-019-01493-y</doi><tpages>8</tpages></addata></record> |
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title | Re-irradiation for humeral epicondylitis |
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