Serological evidence of Rift Valley fever virus infection in slaughtered ruminants in Nigeria

The risk of exposure of slaughterhouse workers to Rift Valley fever (RVF) virus-infected animals in Nigeria was assessed by determining the prevalence of anti-RVF IgM in cattle, goats and sheep slaughtered in a major abattoir in Ibadan, Nigeria. Blood samples were collected from 290 animals in Bodij...

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Bibliographic Details
Published in:Journal of immunoassay & immunochemistry 2019-07, Vol.40 (4), p.367-377
Main Authors: Opayele, Adewale Victor, Ndiana, Linda Amarachi, Odaibo, Georgina Njideka, Olaleye, David Olufemi
Format: Article
Language:English
Subjects:
abattoir
Abattoirs
Animal populations
Animals
Antibodies
Blood
Cattle
Coccidioidomycosis
Enzyme-Linked Immunosorbent Assay
Female
Goats
Immunoglobulin M
Immunoglobulin M - blood
Immunoglobulin M - immunology
Infections
Livestock
Male
Nigeria
Occupational exposure
Outbreaks
Polymerase chain reaction
Ribonucleic acid
Rift Valley fever
Rift Valley Fever - blood
Rift Valley Fever - immunology
Rift Valley fever virus
Rift Valley fever virus - immunology
RNA
RNA viruses
RNA-directed DNA polymerase
Samples
Sheep
Statistical analysis
Statistical methods
Vector-borne diseases
Viral diseases
Viruses
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Summary:The risk of exposure of slaughterhouse workers to Rift Valley fever (RVF) virus-infected animals in Nigeria was assessed by determining the prevalence of anti-RVF IgM in cattle, goats and sheep slaughtered in a major abattoir in Ibadan, Nigeria. Blood samples were collected from 290 animals in Bodija Municipal abattoir, Ibadan, Nigeria in January and February 2017 and analyzed for the presence of RVF virus using IgM Enzyme-Linked Immunosorbent Assay (ELISA) and Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) for detection of the virus RNA. Descriptive statistics was used to analyze data. Overall, an IgM prevalence of 0.7% (2/290) was found among the blood samples of the animals, suggesting recent exposure to the virus. Antibody was detected in the sera from a cow and one goat. RVF virus RNA was not detected in the 2 IgM positive blood samples. There was no statistically significant relationship between RVF IgM infection and some variables of the animals, including age, sex and breed (p ≥ 0.05). Results of this study indicate active RVF virus transmission in domestic livestock in Nigeria. The study emphasizes the need to embark on monitoring of human and animal populations to prevent outbreak of the virus in the country.
ISSN:1532-1819
1532-4230
DOI:10.1080/15321819.2019.1609498