Recent advances in microbial production of malic acid from renewable byproducts

In the last few years, ecofriendly malic acid production has received a potential platform for the bio-based chemicals to replace the dependency of fossil based resources. The main goal of this paper is to explore the feasibility of efficient production of malic acid from cost effective alternative...

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Bibliographic Details
Published in:Reviews in environmental science and biotechnology 2019-09, Vol.18 (3), p.579-595
Main Authors: Iyyappan, J., Baskar, G., Gnansounou, Edgard, Pandey, Ashok, Raaman, Jeganathan Kenthorai, Bharathiraja, B., Praveenkumar, R.
Format: Article
Language:English
Subjects:
Acid production
Acids
Atmospheric Protection/Air Quality Control/Air Pollution
Biosynthesis
By products
Byproducts
Continuous production
Dependence
Earth and Environmental Science
Environment
Environmental Engineering/Biotechnology
Fermentation
Glycerol
Maleic acid
Malic acid
Microbiology
Microorganisms
Organic chemistry
Review Paper
Reviews
Strains (organisms)
Substrates
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Summary:In the last few years, ecofriendly malic acid production has received a potential platform for the bio-based chemicals to replace the dependency of fossil based resources. The main goal of this paper is to explore the feasibility of efficient production of malic acid from cost effective alternative renewable byproducts as feedstock. To replace the traditional method of malic acid production from petroleum-based compounds such as maleic acid, the efficiency of fermentation technology for malic acid production using various microorganisms has been improved. To date, glucose is designated as the best substrate for malic acid production. However, few reviews concerning about malic acid production by employing various microbial strains were reported. The current knowledge on the biosynthesis of malic acid has assisted to improve malic acid production using various microbial strains. But, there is still need for the continuous production and replacement of low-cost substrates to increase the yield of malic acid. This review provides an overview about progress, achievements, merits, challenges and future perspectives in malic acid production from cost effective alternative substrates. Thus, malic acid production can be economical using renewable byproducts like crude glycerol by employing appropriate microorganism.
ISSN:1569-1705
1572-9826
DOI:10.1007/s11157-019-09503-2