Ethnic differences in intrahepatic lipid and its association with hepatic insulin sensitivity and insulin clearance between men of black and white ethnicity with early type 2 diabetes

Intrahepatic lipid (IHL) is linked with reduced hepatic insulin sensitivity and insulin clearance. Despite their high risk for type 2 diabetes (T2D), there have been limited investigations of these relationships in black populations. We investigated these relationships in 18 white European (WE) and...

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Bibliographic Details
Published in:Diabetes, obesity & metabolism obesity & metabolism, 2019-09, Vol.21 (9), p.2163-2168
Main Authors: Hakim, Olah, Bello, Oluwatoyosi, Bonadonna, Riccardo C., Mohandas, Cynthia, Shojaee‐Moradie, Fariba, Jackson, Nicola, Boselli, Linda, Whitcher, Brandon, Shuaib, Haris, Alberti, Kurt George M. M., Peacock, Janet L., Umpleby, Anne Margot, Charles‐Edwards, Geoffrey, Amiel, Stephanie A., Goff, Louise M.
Format: Article
Language:English
Subjects:
African
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Ethnicity
Glucose
hepatic fat
Insulin
insulin clearance
insulin sensitivity
lipotoxicity
Liver
Magnetic resonance imaging
Mens health
Minority & ethnic groups
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Summary:Intrahepatic lipid (IHL) is linked with reduced hepatic insulin sensitivity and insulin clearance. Despite their high risk for type 2 diabetes (T2D), there have been limited investigations of these relationships in black populations. We investigated these relationships in 18 white European (WE) and 18 black West African (BWA) men with T2D
ISSN:1462-8902
1463-1326
DOI:10.1111/dom.13771