Reduction in Omega-6 to Omega 3 ratio and improvement in blood lipid profiles in flaxseed fed Hanwoo steer and human

• Published in: Journal of environmental biology 2019-07, Vol.40 (4), p.655-660
• Main Authors: Song, Y.H., Kin, J.S., Um, K.H., Park, H.J., Chol, Y.S., Lee, H.S., Park, B.S., Shin, J.S.
• Format: Article
• Language: English
• Subjects: Animals; Beef; Blood; Blood glucose; Cattle; Cholesterol; Clinical trials; Density; Diet; Disease; Environmental science; Fatty acid composition; Fatty acids; Feeding; Feeds; Food; Glucose; High density lipoprotein; Human subjects; Jugular vein; Lipids; Livestock; Medical research; Metabolism; Metabolites; Oleic acid; Seeds; Slaughter; Triglycerides
• ISSN: 0254-8704; 2394-0379
• DOI: 10.22438/jeb/40/4/MRN-1037

Aim : To determine the effect of feeding flaxseed on Omega-6 to Omega-3 ratio (n-6/n-3) in Korean native steers (Hanwoo) and effect of flaxseed-fed beef consumption on reducing blood lipid profile and glucose in normal human. Methodology : A total of 60 Hanwoo steers (750 kg b.wt.) were assigned three treatments (20 per treatment). Each treatment group was divided into C (control, feeding basal diets without flaxseed for 40 days before slaughter), FS5 (feeding 5% flaxseed for 60 days before slaughter), and FS7.4 (feeding 7.4% flaxseed for 40 days before slaughter). Fatty acid composition from Hanwoow jugular vein and beef loin were analyzed. Clinical trials were carried out to investigate the effect of consu mption of flaxseed-fed beef loin on blood lipid profile and glucose in twenty human subjects. Results : n-6/n-3 ratio in the blood and beef loin of Hanwoo steers were lowered to 2.262.27 and 3.67-3.71 in the FS group, respectively, compared with the other groups. Oleic acid level in the blood and beef loin of Hanwoo steers increased to 40.12-42.01 and 52.27-52.79%, respectively, compared with other groups. Blood triacylglycerol, total cholesterol, and low-density lipoprotein-cholesterol levels in normal human fed with FS beef loin reduced by 25.35, 5.22, and 17.59%, compared to those before intake of beef loin. Blood high density lipoprotein-cholesterol (HDL-C) level in normal human fed with FS beef loin was increased by 6.07%. In human subjects fed with FS and C beef loin, blood glucose level was decreased by 6.42 and 11.82%, respectively. Interpretation : The results demonstrated that feeding 5 and 7.4% flaxseed to Hanwoo steers for 40 to 60 days before slaughter could lower n-6 to n-3 ratio and inhance oleic acid in the blood and beef loin. Further, consumption of flaxseed-fed beef loin by human subjects could improve blood lipid profile.