Pathophysiology and Urinary System Cancer: An Overview of the most important Herbal Plants and Natural Antioxidants on Kidney and Bladder Disorders

• Published in: Research journal of pharmacy and technology 2019, Vol.12 (2), p.972-980
• Main Authors: Kheirollahi, Abdolreza, Hasanvand, Afshin, Abbaszadeh, Saber, Safarabadi, Arash momeni, Moghadasi, Mona
• Format: Article
• Language: English
• Subjects: Bladder cancer; Cancer therapies; Diabetes; Disease prevention; Flavonoids; Herbal medicine; Hypertension; Kidney cancer; Kidney diseases; Metastasis; Skin; Tumors; Urogenital system
• ISSN: 0974-3618; 0974-360X; 0974-306X
• DOI: 10.5958/0974-360X.2019.00161.6

The information in this review study was obtained from the articles published in databases such as Iran Medex, Irandoc, Institute for Scientific Information, PubMed, Scopus, the Web of Science, Scientific Information Database, Magiran, and Google Scholar using the search words urology, urinary system, urinary system cancer, renal cell carcinoma, renal cell carcinoma classification, bladder cancer and its types, herbal drugs affecting the urinary tract, medicinal plants and bladder cancer, medicinal drugs affecting renal disorders, effects of herbal therapy on renal cell carcinoma in humans and animals, effect of extracts and essential oils of medicinal plants affecting kidney and bladder tissues in mice and humans, and effect of extracts and essential oils of medicinal plants affecting kidney and bladder damage. According to studies, medicinal plants produce the most protective effects against renal damage caused by synthetic drugs probably due to the strong antioxidant properties and the presence of many active plant ingredients, including flavonoids and phenolic compounds. [...]there is a significant relationship between the components of the polyphenol in the extract and its antioxidant activity69-73. [...]they produce inhibitory effects against many types of the cancer cells, including those in the kidneys and the bladder53-73. Medicinal plants have been demonstrated to fight the disorders of the urinary system, the bladder, the kidneys, and the liver as well as various infections in the body due to the presence of antioxidant compounds, bioactive compounds, phenols, flavonoids, and anthocyanins, making it possible to supply herbal drugs in complementary medicine. [...]these medicinal plants may be able to deal with these disorders due to containing phenolic compounds and inducing antioxidant and anti-cancer activities, and are most probably a good candidate for herbal drugs 81-89.