Structure, function, and fate of the BlaR signal transducer involved in induction of (beta)-lactamase in Bacillus licheniformis

The structure, function and fate of the BlaR membrane-spanning protein that is essential for the induction of beta-lactamase in Bacillus licheniformis were investigated by genetic dissection. Alterations of BlaR affecting conserved secondary structures of the penicillin sensor and specific sites of...

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Bibliographic Details
Published in:Journal of bacteriology 1992-10, Vol.174 (19), p.6171
Main Authors: Zhu, Yingfang, Englebert, Serge, Joris, Bernard, Lampen, J Oliver
Format: Article
Language:English
Subjects:
Bacteriology
Biochemistry
Proteins
Online Access:Get full text
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Summary:The structure, function and fate of the BlaR membrane-spanning protein that is essential for the induction of beta-lactamase in Bacillus licheniformis were investigated by genetic dissection. Alterations of BlaR affecting conserved secondary structures of the penicillin sensor and specific sites of the transducer annihilate beta-lactamase inducibility.
ISSN:0021-9193
1098-5530