Two "wild type" variants of Escherichia coli sigma70: Context-dependent effects of the identity of amino acid 149

The identity of amino acid 149 of Escherichia coli sigma(70) has been reported variably as either arginine or aspartic acid. We show that the behavior of both a region 1.2 deletion and a single-amino-acid substitution at position 122 are greatly affected by the identity of amino acid 149.

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Bibliographic Details
Published in:Journal of bacteriology 2002-02, Vol.184 (4), p.1192
Main Authors: Baldwin, Nicole E, McCracken, Andrea, Dombroski, Alicia J
Format: Article
Language:English
Subjects:
Amino acids
Bacteria
Bacteriology
Effects
Online Access:Get full text
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Description
Summary:The identity of amino acid 149 of Escherichia coli sigma(70) has been reported variably as either arginine or aspartic acid. We show that the behavior of both a region 1.2 deletion and a single-amino-acid substitution at position 122 are greatly affected by the identity of amino acid 149.
ISSN:0021-9193
1098-5530