Comparison of the antimicrobial activity of the phyto-constituents obtained from the stem bark and leaf extracts of Phyllanthus emblica L. against different strains of Staphylococcus aureus and Salmonella typhi

• Published in: Research journal of pharmacology and pharmacodynamics 2018-04, Vol.10 (2), p.53-60
• Main Authors: Adak, Serene, Chakraborty, Dipesh, Maji, Himangshu S., Basu, Satakshi, Roy, Pradip, Mitra, Sutanuka, Mukherjee, Nabanita, Barik, Samarendra, Goswami, Arunava
• Format: Article
• Language: English
• Subjects: Antimicrobial agents; Bacteria; Chromatography; Constituents; Ethanol; Experiments; Flavonoids; Gram-positive bacteria; Herbal medicine; Medical research; Pathogens; Phytochemicals; Salmonella; Studies
• ISSN: 0975-4407; 2321-5836
• DOI: 10.5958/2321-5836.2018.00009.5

Clinical use of antibiotics and chemotherapeutics occasionally results human natural system hazards by inhibiting protein synthesis or by misbalancing of natural flora in associated with adverse effects like inflammation, immune-suppression, hypersensitivity, weakness, diarrhoea and many more (Ahmad et al.,1998). [...]traditional folklore plant extracts have been a major concern for experimental development by the modem Bio-science and proposed from the ancient time to be used as antimicrobial therapeutics (Del Campo et al., 2000). The high nutrition value and enrichment with vitamin C, minerals (such as calcium, phosphorus, iron etc.), amino acids, carotene, thiamine, riboflavin, and niacin, other flavonoids and fibre contain makes Amla attractive for scientific research (Srinivasan 1994, D.A Dhale 2012). Phytochemical screening Preliminary analysis of chemical composition of extracts was conducted following the standardized methods of Sofoworaet al.,1993, Brain and Turner et al.,1975, Ushie and Adamu et al.,2010 and Ushieet al.,2012, Trease and Evan et al.,1989 to identify the presence of Secondary Metabolites (Alkaloids, Anthraquinones, Flavonoids, Tannins, Saponins, Glycosides, Cardiac glycosides, Terpenes) and to detect the presence of acidic compound, amino acid, protein carbohydrate, alurone grains, cellulose, lignin; the experiments suggested in Pharmacognosy Paperback was followed. 2.3.1. The antibiotics resistance to an antimicrobial agent was almost impossible when application is done in a repeated manner (Ekhaise and Okoruwa et al, 2001). [...]phytochemical extract of these types of folklore plants could be significant ethno botanically for the use of these antimicrobial purposes. 4.