Pharmacognostic Review on Datura

According to Haritasamhita, datura root is crushed in water and strained the liquid. Organophosphate poisoning : Since D. stramonium contains atropine and other anticholinergic compounds, it is a useful remedy for the central cholinergic symptoms of organophosphate (OP) poisoning. According to their...

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Bibliographic Details
Published in:Research journal of pharmacology and pharmacodynamics 2018-10, Vol.10 (4), p.171-178
Main Authors: Kadam, S. D., Chavhan, S. A., Shinde, S. A., Sapkal, P. N.
Format: Article
Language:English
Subjects:
Analgesics
Asthma
Ayurvedic medicine
Health services
Herbal medicine
Prenatal development
Seeds
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Summary:According to Haritasamhita, datura root is crushed in water and strained the liquid. Organophosphate poisoning : Since D. stramonium contains atropine and other anticholinergic compounds, it is a useful remedy for the central cholinergic symptoms of organophosphate (OP) poisoning. According to their experiment, D. stramonium seeds were heated in water to make 2 mg/mL atropine solution and administered to male rats as a single intraperitoneal injection 5 min before the subcutaneous injection of 25 mg/kg of dichlorvos. Maximum activity was observed when the extract was administered in doses of 3-hour intervals. Since the extract of D. Stramonium inhibited the carrageenan-induced edema that involves the release of histamine and serotonin in the first phase, release of histamine and serotonin in the first phase, the inhibitory effect of the extracts could be partly due to inhibition of mast cell mediator release[21].
ISSN:0975-4407
2321-5836
DOI:10.5958/2321-5836.2018.00032.0