Pharmacological Profile of Terminalia chebula Retz. and Willd. (Haritaki) in Ayurveda with Evidences

According to World Health Organization, about 80% of world population relies chiefly on plant based traditional medicine for their primary healthcare need. [...]it is advised to avoid during pregnancy. Ethanedioic acid and ellagic acid isolated from butanol fraction of Terminalia chebula fruit extra...

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Bibliographic Details
Published in:Research journal of pharmacology and pharmacodynamics 2018-07, Vol.10 (3), p.115-124
Main Authors: Meher, Sudhanshu Kumar, Panda, Purnendu, Das, Banmali, Bhuyan, G. C., Rath, K. K.
Format: Article
Language:English
Subjects:
Ayurvedic medicine
Clinical trials
Flavonoids
Fruits
Herbal medicine
Leaves
Metabolites
Phytochemicals
Trees
Wound healing
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Summary:According to World Health Organization, about 80% of world population relies chiefly on plant based traditional medicine for their primary healthcare need. [...]it is advised to avoid during pregnancy. Ethanedioic acid and ellagic acid isolated from butanol fraction of Terminalia chebula fruit extract had strong antibacterial activity against intestinal bacteria, Clostridium perfingens and Escherichia coli47. iii) GA and its ethyl ester isolated from ethanolic extract of Terminalia chebula showed antimicrobial activity against methicillin-resistant Staphylococcus aureus (S. aureus)48. iv) Ripe seeds of Terminalia chebula also exhibited strong antibacterial activity against S. aureus49. v) The aqueous extract of Terminalia chebula strongly inhibited the growth of Streptococcus mutans, salivary bacteria50. vi) Diffusate of Terminalia chebula showed an inhibitory effect against strain X-100 of the bacterium Xanthomonas campestris pv.citri indicating its usefulness for the management of citrus canker disease which is a disease affecting citrus species of plants51. vii) It has also growth inhibitory action against Salmonella typhi, 52 Klebsiella53, Shigella47 and intestinal bacteria50. viii) Growth inhibitory activity of active component from Terminalia chebula fruits against intestinal bacteria.54 ix) Ethanol extract of Terminalia chebula fruit showed strong antibacterial activity against multidrugresistant uropathogenic Escherichia coli and phenolics were found to be responsible for this antibacterial activity55,56 x) A study on Terminalia chebula fruit extract treated cotton fabric for health care application showed anti microbial activity57 9. [...]extensive investigation is needed to exploit its therapeutic ability to combat other various medical situations.
ISSN:0975-4407
2321-5836
DOI:10.5958/2321-5836.2018.00023.X