Development and Validation for estimation of Abiraterone acetate in Bulk and Pharmaceutical Dosage Form by UPLC

Mobile phase 0.01N NaHPO4: Acetonitrile in the ratio of 60:40v/v and flow rate were maintained at 0.3 ml/min, detection wave length was 235 nm, and column temperature was set to 30°C. System suitability parameters were studied by injecting the standard six times and results were well under the accep...

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Published in:Research journal of pharmacy and technology 2019, Vol.12 (6), p.3029-3032
Main Authors: Goud, V. Mohan, Rani, B Sandhya, Sharma, JVC, Sirisha, P.
Format: Article
Language:English
Subjects:
Chromatography
Ions
Prostate cancer
Studies
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creator Goud, V. Mohan
Rani, B Sandhya
Sharma, JVC
Sirisha, P.
description Mobile phase 0.01N NaHPO4: Acetonitrile in the ratio of 60:40v/v and flow rate were maintained at 0.3 ml/min, detection wave length was 235 nm, and column temperature was set to 30°C. System suitability parameters were studied by injecting the standard six times and results were well under the acceptance criteria. [...]our plan to develop a new economic UPLC method for routine analysis. Khdera A, Darwish I, Bamanea F, Analysis of abiraterone stress degradation behavior using liquid chromatography coupled to ultraviolet detection and electrospray ionization mass spectrometry.
doi_str_mv 10.5958/0974-360X.2019.00512.2
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subjects Chromatography
Ions
Prostate cancer
Studies
title Development and Validation for estimation of Abiraterone acetate in Bulk and Pharmaceutical Dosage Form by UPLC
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