Conjugation of the Alkaloid Anabasine to Coumarins

The possibility of using the alkaloid anabasine in Mannich aminomethylation of coumarins was studied. Anabasine-coumarin conjugates in which the benzopyrone core was conjugated to anabasine through a methylene linker were synthesized.

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Bibliographic Details
Published in:Chemistry of natural compounds 2019-07, Vol.55 (4), p.628-631
Main Authors: Bondarenko, S. P., Mrug, G. P., Vinogradova, V. I., Khilya, V. P., Frasinyuk, M. S.
Format: Article
Language:English
Subjects:
Alkaloids
Conjugation
Coumarin
Coumarins
Medicine
Organic Chemistry
Pharmacy
Plant Sciences
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Description
Summary:The possibility of using the alkaloid anabasine in Mannich aminomethylation of coumarins was studied. Anabasine-coumarin conjugates in which the benzopyrone core was conjugated to anabasine through a methylene linker were synthesized.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-019-02765-w