Survey of current practices from the International Stereotactic Body Radiotherapy Consortium (ISBRTC) for head and neck cancers

To provide a multi-institutional description of current practices of stereotactic body radiotherapy (SBRT) for head and neck cancer. 15 international institutions with significant experience in head and neck SBRT were asked to complete a questionnaire covering clinical and technical factors. SBRT is...

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Bibliographic Details
Published in:Future oncology (London, England) England), 2017-03, Vol.13 (7), p.603-613
Main Authors: Karam, Irene, Yao, Min, Heron, Dwight E, Poon, Ian, Koyfman, Shlomo A, Yom, Sue S, Siddiqui, Farzan, Lartigau, Eric, Cengiz, Mustafa, Yamazaki, Hideya, Hara, Wendy, Phan, Jack, Vargo, John A, Lee, Victor, Foote, Robert L, Harter, K William, Lee, Nancy Y, Sahgal, Arjun, Lo, Simon S
Format: Article
Language:English
Subjects:
ablation
Cancer therapies
Chemotherapy
Clinical trials
Consortia
Dose Fractionation
Female
Follow-Up Studies
Head & neck cancer
head and neck cancer
Head and Neck Neoplasms - diagnosis
Head and Neck Neoplasms - epidemiology
Head and Neck Neoplasms - radiotherapy
Health Care Surveys
Humans
Male
Neoplasm Staging
Patients
patterns of practice
Radiation Dosage
Radiation therapy
Radiosurgery - adverse effects
Radiosurgery - methods
Radiotherapy Planning, Computer-Assisted
SBRT
Standard of Care
stereotactic
Tumors
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Summary:To provide a multi-institutional description of current practices of stereotactic body radiotherapy (SBRT) for head and neck cancer. 15 international institutions with significant experience in head and neck SBRT were asked to complete a questionnaire covering clinical and technical factors. SBRT is used 10-100% of the time for recurrent primary head and neck cancer, and 0-10% of the time in newly diagnosed disease. Five centers use a constraint for primary disease of 3-5 cm and 25-30 cc. Nine institutions apply a clinical target volume expansion of 1-10 mm and 14 use a planning target volume margin of 1-5 mm. Fractionation regimens vary between 15 and 22 Gy in 1 fraction to 30-50 Gy in 5 or 6 fractions. The risk of carotid blowout quoted in the re-irradiation setting ranges from 3 to 20%. There is considerable heterogeneity in patient selection and techniques in head and neck SBRT practice among experienced centers.
ISSN:1479-6694
1744-8301
DOI:10.2217/fon-2016-0403