FREEZE-ALL STRATEGY: PREGNANCY RATE, OBSTETRICAL PROGNOSIS AND ETHICAL CONSIDERATIONS - REVIEW EVALUATING 278.000 NEWBORNS AFTER ART

Uterine contractility can also be increased in the same cycle, and the implantation window is sometimes missed at the time of transfer27. 2.Placentation and associated obstetric complications In addition to the number of pregnancies that are lower in the fresh embryo group, it appears that ovarian h...

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Published in:Research and science today 2019-01, p.102-119
Main Authors: Mihai, Diana, Velişcu, Andreea, Comandaşu, Diana Elena, Coroleucă, Cătălin Bogdan, Coroleucă, Ciprian Andrei, Mehedinţu, Claudia, Bordea, Alina Elena, Braga, Mihaela, Nadă, Elena Silvia, Bratu, Ovidiu Gabriel
Format: Article
Language:English
Subjects:
Age
Birth rate
Complications
Contractility
Cryopreservation
Division
Drug development
Drugs
Embryo transfer
Embryos
Endometriosis
Ethics
Fetuses
Gametocytes
Gestational age
Hatching
Hernia
Hypertension
Implantation
In vitro fertilization
Infants
Infertility
Neonates
Obstetrics
Oocytes
Patients
Placenta
Pregnancy
Pregnancy complications
Prognosis
Regression analysis
Risk analysis
Risk factors
Small for gestational age
Stimulation
Ultrasonic imaging
Uterus
Weight reduction
Windows (intervals)
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Summary:Uterine contractility can also be increased in the same cycle, and the implantation window is sometimes missed at the time of transfer27. 2.Placentation and associated obstetric complications In addition to the number of pregnancies that are lower in the fresh embryo group, it appears that ovarian hyperstimulation drugs also affect the development of pregnancy, placenta is altered in the case of ET in the same stimulation cycle28 and so many obstetric complications associated with this process occur29. [...]in the case of frozen embryos, a better pregnancy prognosis [95% CI] was observed: the fetus had a lower risk of being small for gestational age RR: 0.59, reduced gestational weight RR: 0.74, premature delivery RR: 0.74, but higher risk of RR: 1.10 cesarean and larger for gestational age RR: 1.4930. [...]the interesting discovery is that intrinsic factors rather than extrinsic factors influence the embryo's division process and the occurrence of the twin pregnancy after single transfer50. Logistic regression analysis showed that patients under 35 years old with high quality recovered oocytes and increased number of day 3 or 5 embryos of superior quality had the highest monozygotic pregnancy rates (3.1%), regardless of use ICSI or assisted hatching [p
ISSN:2247-4455
2285-9632