Effects of cellulose nanofibrils on dialdehyde carboxymethyl cellulose based dual responsive self-healing hydrogel

A self-healing hydrogel containing acylhydrazone bond and disulfide bond with pH and redox dual responses was prepared by crosslinking dialdehyde carboxymethyl cellulose (DCMC) with 3,3′-dithiobis(propionohydrazide) (DTP). The pH, gelator concentration and oxidation degree of DCMC affected the forma...

Full description

Saved in:
Bibliographic Details
Published in:Cellulose (London) 2019-11, Vol.26 (16), p.8813-8827
Main Authors: Wang, Ying, Xiao, Guifa, Peng, Yangyang, Chen, Liheng, Fu, Shiyu
Format: Article
Language:English
Subjects:
Biocompatibility
Bioorganic Chemistry
Carboxymethyl cellulose
Cellulose
Ceramics
Chemistry
Chemistry and Materials Science
Composites
Compressive strength
Crosslinking
Glass
Hydrogels
Nanofibers
Natural Materials
Organic Chemistry
Original Research
Oxidation
Physical Chemistry
Polymer Sciences
Sustainable Development
Toxicity testing
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A self-healing hydrogel containing acylhydrazone bond and disulfide bond with pH and redox dual responses was prepared by crosslinking dialdehyde carboxymethyl cellulose (DCMC) with 3,3′-dithiobis(propionohydrazide) (DTP). The pH, gelator concentration and oxidation degree of DCMC affected the formation of DCMC-based self-healing hydrogels seriously. Interestingly, addition of cellulose nanofibers (CNFs) improved the mechanical property of the DCMC-based self-healing hydrogel and its efficiency. When 1.0 wt% CNFs was added in hydrogel preparation, the compressive strength (1.05 MPa) of the composite hydrogel increased by 275% and its strain rose to 74.6%. The healing rate of hydrogel containing 1.0 wt% CNFs was 82.7% at 0.5 h and 89.9% at 1 h, which was much faster than that of original hydrogel (51.6% at 0.5 h and 58.5% in 1 h). DCMC-based dual responsive self-healing hydrogel showed good biocompatibility confirmed by cytotoxicity test, which is potential to implement in medial field. Graphic abstract
ISSN:0969-0239
1572-882X
DOI:10.1007/s10570-019-02673-w