New fluorous gelators for perfluorodecalin

[Display omitted] •Fluorous gelators for perfluorodecalin (PFD) were synthesized.•Fluoroalkyl chains were introduced to the known gelators.•PFD turned into gel by using the fluoroalkyl-containing anthraquinone.•NIH 3T3 cells were cultured in the presence of prepared fluorous gels of PFD. Fluorous ge...

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Bibliographic Details
Published in:Journal of fluorine chemistry 2019-06, Vol.222-223, p.24-30
Main Authors: Miyajima, Hiroki, Kasuya, Maria Carmelita Z., Hatanaka, Kenichi
Format: Article
Language:English
Subjects:
Anthraquinone
Anthraquinones
Biocompatibility
Biomedical materials
Cell culture
Chains
Cytotoxicity
Fluorous gel
Gelator
Gels
Organic chemistry
Perfluorodecalin
Synthesis
Toxicity
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Summary:[Display omitted] •Fluorous gelators for perfluorodecalin (PFD) were synthesized.•Fluoroalkyl chains were introduced to the known gelators.•PFD turned into gel by using the fluoroalkyl-containing anthraquinone.•NIH 3T3 cells were cultured in the presence of prepared fluorous gels of PFD. Fluorous gels of perfluorodecalin (PFD) were prepared using chemically synthesized fluorous gelators. To enhance the fluorophilicity of gelators, fluoroalkyl chains were introduced to the alkyl chains of known gelators. The synthesized fluoroalkyl-containing anthraquinone formed gels of PFD. The prepared gel of PFD was used for cell culture and the cytotoxicity of the gel was assessed in view of its potential biomedical application.
ISSN:0022-1139
1873-3328
DOI:10.1016/j.jfluchem.2019.04.008