Morphine, Hypotension, and Intraventricular Hemorrhage in the Ventilated Premature Infant

In reference to study titled Morphine, Hypotension, and Adverse Outcomes Among Preterm Neonates: Who's to Blame by Schmidt et al, Perlman finds that the question of whether ventilated infants should be routinely administered narcotics such as morphine remains controversial. He observes, among o...

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Bibliographic Details
Published in:Pediatrics (Evanston) 2005-05, Vol.115 (5), p.1416-1418
Main Author: Perlman, Jeffrey M
Format: Article
Language:English
Subjects:
Analgesics, Opioid - adverse effects
Analgesics, Opioid - therapeutic use
Cardiovascular disease
Care and treatment
Causes of
Cerebral Hemorrhage - etiology
Complications and side effects
Dosage and administration
Drug therapy
Hemorrhage
Humans
Hypotension - chemically induced
Hypotension - complications
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases - etiology
Infants (Premature)
Intraventricular hemorrhage
Leukomalacia, Periventricular - etiology
Morphine
Morphine - adverse effects
Morphine - therapeutic use
Narcotics
Neonatal care
Pain - prevention & control
Pain in children
Pediatric pain
Pediatrics
Premature infants
Respiration, Artificial
Side effects
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Summary:In reference to study titled Morphine, Hypotension, and Adverse Outcomes Among Preterm Neonates: Who's to Blame by Schmidt et al, Perlman finds that the question of whether ventilated infants should be routinely administered narcotics such as morphine remains controversial. He observes, among other things, that hypotension associated with morphine administration in the smallest premature infants could increase the propensity for white-matter injury, which may have gone undetected based on the end points in this study
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.2005-0501