Lung cancer biobank in Eastern C hina

BackgroundThe prevalence of lung cancer, a highly complex neoplasm, increases annually. Thus, a lung cancer biobank, which stores lung cancer tissue and blood matched according to standard methods, is needed to advance lung cancer research and develop promising therapies.MethodsTo accomplish this ai...

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Bibliographic Details
Published in:Thoracic cancer 2015-01, Vol.6 (1), p.58-63
Main Authors: Yu, Keke, Zhang, Jie, Li, Xin, Xu, Lei, Zhang, Ye, Xing, Jie, Shao, Jinchen, Zhu, Lei, Liu, Jinguo, Zhao, Lanxiang, Han, Baohui
Format: Article
Language:English
Subjects:
Cancer therapies
Deoxyribonucleic acid
DNA
Electronic health records
Hospitals
Information management
Library collections
Lung cancer
Medical records
Medical research
Mutation
Pathology
Patients
Proteins
Quality control
Software
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Summary:BackgroundThe prevalence of lung cancer, a highly complex neoplasm, increases annually. Thus, a lung cancer biobank, which stores lung cancer tissue and blood matched according to standard methods, is needed to advance lung cancer research and develop promising therapies.MethodsTo accomplish this aim, we implemented standardized procedures for tissue samples and patient information acquired from consenting donors. The banked tissue includes blood, pleural effusions, and surgical resection samples. An independent information management system was used to match samples and collect data, including clinical cancer manifestation, laboratory tests, and de‐identified data about cancer patients.ResultsFrom 2009 to 2013, more than 2000 lung cancer cases were collected. At this time, we have more than 10 000 biological samples stored in our biobank. DNA, ribonucleic acid (RNA), and protein quality were confirmed to be appropriate for clinical and basic research.ConclusionOur standardized, large‐scale lung cancer biobank offers high quality cancer research samples for China and the world.
ISSN:1759-7706
1759-7714
DOI:10.1111/1759-7714.12144