Novel catheterization technique for the in vivo measurement of pulmonary vascular responses in rats

A novel cardiac catheterization technique was devised to investigate the pulmonary arterial pressure-blood flow relationship in intact spontaneously breathing rats (ISBR) under physiological conditions with constant left atrial pressure and controlled blood flow within the normal range. Observations...

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Bibliographic Details
Published in:American journal of physiology. Heart and circulatory physiology 1998-04, Vol.43 (4), p.H1218-H1229
Main Authors: HYMAN, A. L, QINGZHONG HAO, TOWER, A, KADOWITZ, P. J, CHAMPION, H. C, GUMUSEL, B, LIPPTON, H
Format: Article
Language:English
Subjects:
Air breathing
Biological and medical sciences
Blood pressure
Cardiology
Circulatory system
Fundamental and applied biological sciences. Psychology
Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics
Rodents
Vertebrates: respiratory system
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Summary:A novel cardiac catheterization technique was devised to investigate the pulmonary arterial pressure-blood flow relationship in intact spontaneously breathing rats (ISBR) under physiological conditions with constant left atrial pressure and controlled blood flow within the normal range. Observations using this new technique in vivo were contrasted with data derived with isolated perfused rat lungs in vitro.
ISSN:0363-6135
1522-1539