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Melatonin as an effective protector against doxorubicin-induced cardiotoxicity
Liu et al explored the protective effects of melatonin and its analogs, 6-hydroxymelatonin and 8-methoxy-2-propionamidotetralin, on the survival of doxorubicin-treated mice and on doxorubicin-induced cardiac dysfunction, ultrastructural alterations, and apoptosis in mouse hearts.
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Published in: | American journal of physiology. Heart and circulatory physiology 2002-07, Vol.52 (1), p.H254-H263 |
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container_end_page | H263 |
container_issue | 1 |
container_start_page | H254 |
container_title | American journal of physiology. Heart and circulatory physiology |
container_volume | 52 |
creator | XUWAN LIU ZHONGYI CHEN CHU CHANG CHUA MA, Yan-Shan YOUNGBERG, George A HAMDY, Ronald CHUA, Balvin H. L |
description | Liu et al explored the protective effects of melatonin and its analogs, 6-hydroxymelatonin and 8-methoxy-2-propionamidotetralin, on the survival of doxorubicin-treated mice and on doxorubicin-induced cardiac dysfunction, ultrastructural alterations, and apoptosis in mouse hearts. |
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Drug treatments</topic><topic>Rodents</topic><topic>Toxicity</topic><topic>Toxicity: cardiovascular system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>XUWAN LIU</creatorcontrib><creatorcontrib>ZHONGYI CHEN</creatorcontrib><creatorcontrib>CHU CHANG CHUA</creatorcontrib><creatorcontrib>MA, Yan-Shan</creatorcontrib><creatorcontrib>YOUNGBERG, George A</creatorcontrib><creatorcontrib>HAMDY, Ronald</creatorcontrib><creatorcontrib>CHUA, Balvin H. 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language | eng |
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source | American Physiological Society Free |
subjects | Antibiotics Biological and medical sciences Cells Drug toxicity and drugs side effects treatment Heart Hormones Medical sciences Pharmacology. Drug treatments Rodents Toxicity Toxicity: cardiovascular system |
title | Melatonin as an effective protector against doxorubicin-induced cardiotoxicity |
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