Influence of heart rate and sympathetic stimulation on arrhythmogenic T wave alternans

We determined the temporal stability of T wave alternans (TWA) during constant rate stimulation and the dependence of alternans on heart rate (HR) and beta-adrenergic stimulation. Although it is established that exercise can provoke microvolt-level TWA in patients at risk for reentrant ventricular a...

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Bibliographic Details
Published in:American journal of physiology. Heart and circulatory physiology 2000-09, Vol.48 (3), p.H1248-H1255
Main Authors: KAUFMAN, Elizabeth S, MACKALL, Judith A, JULKA, Birendra, DRABEK, Carole, ROSENBAUM, David S
Format: Article
Language:English
Subjects:
Biochemistry
Biological and medical sciences
Cardiac dysrhythmias
Cardiology. Vascular system
Circulatory system
Heart
Medical sciences
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Summary:We determined the temporal stability of T wave alternans (TWA) during constant rate stimulation and the dependence of alternans on heart rate (HR) and beta-adrenergic stimulation. Although it is established that exercise can provoke microvolt-level TWA in patients at risk for reentrant ventricular arrhythmias, the mechanisms underlying TWA in humans are not well understood.
ISSN:0363-6135
1522-1539