Transmyocardial revascularization aggravates myocardial ischemia around the channels in the immediate phase

We examined whether transmyocardial revascularization (TMR) relieves myocardial ischemia by increasing regional perfusion via the transmural channels in acute canine experiments. Regional blood flow during transient coronary ligation (2 min) was compared before and 30 min after TMR, and at the third...

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Published in:American journal of physiology. Heart and circulatory physiology 2000-09, Vol.48 (3), p.H1392-H1396
Main Authors: HATTAN, Naoichiro, BAN, Kazunobu, SUMA, Hisayoshi, HANDA, Shunnosuke, KAWADA, Shiaki, HORI, Shingo, IIDA, Atsuo, NAKAZAWA, Hiroe, MORI, Hidezo, TANAKA, Etsuro, ABE, Sumihisa, SEKKA, Takafumi, SUGIO, Yoshinori, MOHAMMED, Minhaz U, SATO, Eriko, SHINOZAI, Yoshiro, ONISHI, Yozo
Format: Article
Language:English
Subjects:
Biological and medical sciences
Coronary vessels
Heart
Medical sciences
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
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Summary:We examined whether transmyocardial revascularization (TMR) relieves myocardial ischemia by increasing regional perfusion via the transmural channels in acute canine experiments. Regional blood flow during transient coronary ligation (2 min) was compared before and 30 min after TMR, and at the third transient ischemia the mid-left ventricle (LV) was cut and immediately frozen along the short axis for the analsysis of NADH fluorescence in the regions around the TMR channels.
ISSN:0363-6135
1522-1539