Low-dose ramipril treatment improves relaxation and calcium cycling after established cardiac hypertrophy

Rapid cooling contractures were used in this study to test whether low-dose ramipril improves sarcoplasmic reticulum (SR) Ca2+ uptake and Na+/Ca2+ exchanger function in isolated hypertrophied rat myocytes. Compensated cardiac hypertrophy was induced by abdominal aortic constriction for 5 wk followed...

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Published in:American journal of physiology. Heart and circulatory physiology 2001-03, Vol.49 (3), p.H1029-H1038
Main Authors: BOATENG, Samuel Y, NAQVI, Ruby U, KOBAN, Maren U, YACOUB, Magdi H, MACLEOD, Kenneth T, BOHELER, Kenneth R
Format: Article
Language:English
Subjects:
Biological and medical sciences
Caffeine
Calcium
Cardiovascular disease
Cardiovascular system
Cells
Clinical trials
Medical sciences
Miscellaneous
Pharmacology. Drug treatments
Proteins
Ribonucleic acid
RNA
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container_end_page H1038
container_issue 3
container_start_page H1029
container_title American journal of physiology. Heart and circulatory physiology
container_volume 49
creator BOATENG, Samuel Y
NAQVI, Ruby U
KOBAN, Maren U
YACOUB, Magdi H
MACLEOD, Kenneth T
BOHELER, Kenneth R
description Rapid cooling contractures were used in this study to test whether low-dose ramipril improves sarcoplasmic reticulum (SR) Ca2+ uptake and Na+/Ca2+ exchanger function in isolated hypertrophied rat myocytes. Compensated cardiac hypertrophy was induced by abdominal aortic constriction for 5 wk followed by administration of ramipril (50 mug.kg-1.
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source American Physiological Society Free
subjects Biological and medical sciences
Caffeine
Calcium
Cardiovascular disease
Cardiovascular system
Cells
Clinical trials
Medical sciences
Miscellaneous
Pharmacology. Drug treatments
Proteins
Ribonucleic acid
RNA
title Low-dose ramipril treatment improves relaxation and calcium cycling after established cardiac hypertrophy
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