Upregulated TRP and enhanced capacitative Ca2+ entry in human pulmonary artery myocytes during proliferation

Golovina, Vera A., Oleksandr Platoshyn, Colleen L. Bailey, Jian Wang, Alisa Limsuwan, Michele Sweeney, Lewis J. Rubin, and Jason X.-J. Yuan. Upregulated TRP and enhanced capacitative Ca+ entry in human pulmonary artery myocytes during proliferation. Am J Physiol Heart Circ Physiol 280: H746-H755, 20...

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Published in:American journal of physiology. Heart and circulatory physiology 2001-02, Vol.49 (2), p.H746-H755
Main Authors: GOLOVINA, Vera A, PLATOSHYN, Oleksandr, BAILEY, Colleen L, JIAN WANG, LIMSUWAN, Alisa, SWEENEY, Michele, RUBIN, Lewis J, YUAN, Jason X.-J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood vessels
Cardiology
Cells
Medical research
Medical sciences
Pneumology
Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases
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Summary:Golovina, Vera A., Oleksandr Platoshyn, Colleen L. Bailey, Jian Wang, Alisa Limsuwan, Michele Sweeney, Lewis J. Rubin, and Jason X.-J. Yuan. Upregulated TRP and enhanced capacitative Ca+ entry in human pulmonary artery myocytes during proliferation. Am J Physiol Heart Circ Physiol 280: H746-H755, 2001.-A rise in cytosolic Ca 21 concentration ([Ca2+]cyt) due to Ca 2 + release from intracellular Ca 21 stores and Ca 21 influx through plasma Ca 21 channels plays a critical role in mitogen-mediated cell growth.
ISSN:0363-6135
1522-1539