Effect of NO on EDHF response in rat middle cerebral arteries

Whereas the actual identity of endothelium-derived hyperpolarizing factor (EDHF) is still not certain, it involves a process requiring the endothelium and eliciting hyperpolarization and relaxation of smooth muscle. It is neither nitrix oxide (NO) nor prostacyclin, and its presence has been demonstr...

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Bibliographic Details
Published in:American journal of physiology. Heart and circulatory physiology 2002-02, Vol.51 (2), p.H734-H738
Main Authors: SCHILDMEYER, Lisa A, BRYAN, Robert M
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood vessels
Brain
Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges
Free radicals
Fundamental and applied biological sciences. Psychology
Rodents
Vertebrates: nervous system and sense organs
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Summary:Whereas the actual identity of endothelium-derived hyperpolarizing factor (EDHF) is still not certain, it involves a process requiring the endothelium and eliciting hyperpolarization and relaxation of smooth muscle. It is neither nitrix oxide (NO) nor prostacyclin, and its presence has been demonstrated in a variety of vessels.
ISSN:0363-6135
1522-1539