Reversible inhibition of cellular respiration by nitric oxide in vascular inflammation

Incubation of rat aortas with endotoxin and interferon-gamma for 24 h rsulted in an aortic oxygen consumption that was substantially inhibited and strongly oxygen dependent (37% inhibition at 160 muM O2 and 62% inhibition at 80 muM 02 relative to untreated aortas).

Saved in:
Bibliographic Details
Published in:American journal of physiology. Heart and circulatory physiology 2001-12, Vol.50 (6), p.H2256
Main Authors: Vilman te Borutaite, Matthias, Anita, Harris, Hatty, Moncada, Salvador, Brown, Guy C
Format: Article
Language:English
Subjects:
Biochemistry
Cells
Coronary vessels
Oxygen
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Incubation of rat aortas with endotoxin and interferon-gamma for 24 h rsulted in an aortic oxygen consumption that was substantially inhibited and strongly oxygen dependent (37% inhibition at 160 muM O2 and 62% inhibition at 80 muM 02 relative to untreated aortas).
ISSN:0363-6135
1522-1539