Postischemic Na+-K+-ATPase reactivation is delayed in the absence of glycolytic ATP in isolated rat hearts

Normalization of intracellular sodium (Nai+) after postischemic reperfusion depends on reactivation of the sarcolemmal Na+-K+-ATPhase. To evaluate the requirement of glycolytic ATP for Na+-K+-ATPase function during postischemic reperfusion, 5-s time-resolution 23Na NMR was performed in isolated perf...

Full description

Saved in:
Bibliographic Details
Published in:American journal of physiology. Heart and circulatory physiology 2001-05, Vol.49 (5), p.H2189-H2195
Main Authors: VAN EMOUS, Jan G, VLEGGEERT-LANKAMP, Carmen L. A. M, NEDERHOFF, Marcel G. J, RUIGROK, Tom J. C, VAN ECHTELD, Cees J. A
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiology. Vascular system
Coronary heart disease
Heart
Medical sciences
NMR
Nuclear magnetic resonance
Potassium
Rodents
Sodium
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Normalization of intracellular sodium (Nai+) after postischemic reperfusion depends on reactivation of the sarcolemmal Na+-K+-ATPhase. To evaluate the requirement of glycolytic ATP for Na+-K+-ATPase function during postischemic reperfusion, 5-s time-resolution 23Na NMR was performed in isolated perfused rat hearts.
ISSN:0363-6135
1522-1539