Activity and responsiveness of the renin-angiotensin system in the aging rat

The systemic renin-angiotensin system (RAS) is suppressed in normal aging, but the activity of the tissue RAS is not well defined. We examined the systemic and intrarenal RAS status of aging normal rats and responses to suppression and stimulation of the production of endogenous ANG II.

Saved in:
Bibliographic Details
Published in:American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2000-11, Vol.48 (5), p.R1787-R1794
Main Authors: THOMPSON, Michele M, OYAMA, Terry T, KELLY, Francis J, KENNEFICK, Thomas M, ANDERSON, Sharon
Format: Article
Language:English
Subjects:
Aging
Biological and medical sciences
Endocrine kidney. Renin-angiotensin-aldosterone system
Fundamental and applied biological sciences. Psychology
Hormones
Kidneys
Rodents
Vertebrates: endocrinology
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The systemic renin-angiotensin system (RAS) is suppressed in normal aging, but the activity of the tissue RAS is not well defined. We examined the systemic and intrarenal RAS status of aging normal rats and responses to suppression and stimulation of the production of endogenous ANG II.
ISSN:0363-6119
1522-1490