Rat trehalase : cDNA cloning and mRNA expression in adult rat tissues and during intestinal ontogeny

A partial rat trehalase cDNA has been cloned and used to examine trehalase mRNA expression. Northern blotting with total RNA from 11 adult rat tissues showed a trehalase transcript only in small intestine, where it was abundant in proximal regions but declined steeply toward the ileum. During develo...

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Bibliographic Details
Published in:American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 1998-05, Vol.43 (5), p.R1220-R1227
Main Authors: OESTERREICHER, T. J, NANTHAKUMAR, N. N, WINSTON, J. H, HENNING, S. J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cloning
Deoxyribonucleic acid
Digestive system
DNA
Fundamental and applied biological sciences. Psychology
Hormones
Intestine. Mesentery
Ribonucleic acid
RNA
Vertebrates: digestive system
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Summary:A partial rat trehalase cDNA has been cloned and used to examine trehalase mRNA expression. Northern blotting with total RNA from 11 adult rat tissues showed a trehalase transcript only in small intestine, where it was abundant in proximal regions but declined steeply toward the ileum. During development, trehalase mRNA was not detectable in jejunum until postnatal day 19 and then increased markedly through day 25.
ISSN:0363-6119
1522-1490