In birds, NHE2 is major brush-border Na+/H+ exchanger in colon and is increased by a low-NaCl diet

We previously reported that mammalian small intestinal and colonic brush borders (BBs) contained both epitheIial Na+/H+ exchangers NHE2 and NHE3. We now show that, in the avian (chicken) colon, NHE2 is the major functional isoform under basal conditions and when stimulated by a low-NaCl diet.

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Bibliographic Details
Published in:American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 1998-06, Vol.43 (6), p.R1659-R1669
Main Authors: DONOWITZ, M, DE LA HORRA, C, CALONGE, M. L, WOOD, I. S, DYER, J, GRIBBLE, S. M, SANCHEZ DE MEDINA, F, TSE, C. M, SHIRAZI-BEECHEY, S. P, ILUNDAIN, A. A
Format: Article
Language:English
Subjects:
Biological and medical sciences
Birds
Diet
Digestive system
Fundamental and applied biological sciences. Psychology
Intestine. Mesentery
Ions
Salt
Vertebrates: digestive system
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Summary:We previously reported that mammalian small intestinal and colonic brush borders (BBs) contained both epitheIial Na+/H+ exchangers NHE2 and NHE3. We now show that, in the avian (chicken) colon, NHE2 is the major functional isoform under basal conditions and when stimulated by a low-NaCl diet.
ISSN:0363-6119
1522-1490