Management of Malignant Melanoma: Best Practices

Background: Melanoma is a commonly occurring cancer in Canada, with an estimated age-standardized incidence of 10 to 13 per 100,000. An estimated 4,300 new cases were diagnosed, and there were 880 reported deaths in 2005. Objective and Conclusion: The Canadian Expert Panel on Malignant Melanoma has...

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Bibliographic Details
Published in:Journal of cutaneous medicine and surgery 2009-03, Vol.13 (2), p.55-73
Main Authors: Smylie, Michael, Claveau, Joël, Alanen, Kenneth, Taillefer, Raymond, George, Ralph, Wong, Ralph, Mason, Warren P.
Format: Article
Language:English
Subjects:
Antineoplastic Agents, Alkylating - therapeutic use
Benchmarking
Best practice
Biological and medical sciences
Brain Neoplasms - secondary
Brain Neoplasms - therapy
Combined Modality Therapy
Dacarbazine - analogs & derivatives
Dacarbazine - therapeutic use
Dermatology
Disease management
Guidelines
Humans
Intraoperative Period
Medical sciences
Melanoma - diagnosis
Melanoma - pathology
Melanoma - surgery
Melanoma - therapy
Neoplasm Invasiveness
Neoplasm Metastasis
Prognosis
Sentinel Lymph Node Biopsy
Skin cancer
Skin Neoplasms - diagnosis
Skin Neoplasms - pathology
Skin Neoplasms - surgery
Skin Neoplasms - therapy
Tumors of the skin and soft tissue. Premalignant lesions
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Summary:Background: Melanoma is a commonly occurring cancer in Canada, with an estimated age-standardized incidence of 10 to 13 per 100,000. An estimated 4,300 new cases were diagnosed, and there were 880 reported deaths in 2005. Objective and Conclusion: The Canadian Expert Panel on Malignant Melanoma has developed best practices to improve the management of malignant melanoma. Sections include recommendations on primary diagnosis, dermatopathologic assessment, and reporting; use of preoperative lymphoscintigraphy and an intraoperative gamma probe to map and biopsy the sentinel lymph node; indications for surgical resection, sentinel node biopsy, and surgery for advanced disease; use of interferon-α adjuvant therapy and treatment options for stage IV disease; and management of central nervous system metastases.
ISSN:1203-4754
1615-7109
DOI:10.2310/7750.2008.08029