Treatment of Focal Hyperhidrosis

Background: Focal hyperhidrosis is not rare, affecting over 2.5% of the population. This condition is often socially and professionally debilitating, leading to significant quality of life impairment. It most commonly involves the axillae, palms, soles, and face. Objective: To review hyperhidrosis a...

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Bibliographic Details
Published in:Journal of Cutaneous Medicine and Surgery 2007-03, Vol.11 (2), p.67-77
Main Authors: Murray, Christian A., Cohen, Joel L., Solish, Nowell
Format: Article
Language:English
Subjects:
Axilla
Biological and medical sciences
Botulinum Toxins, Type A - administration & dosage
Botulinum Toxins, Type A - therapeutic use
Cholinergic Antagonists - therapeutic use
Dermatology
Hand
Humans
Hyperhidrosis - diagnosis
Hyperhidrosis - drug therapy
Hyperhidrosis - physiopathology
Hyperhidrosis - therapy
Injections, Intradermal
Iontophoresis
Lipectomy
Medical sciences
Neuromuscular Agents - administration & dosage
Neuromuscular Agents - therapeutic use
Skin involvement in other diseases. Miscellaneous. General aspects
Sympathectomy
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Summary:Background: Focal hyperhidrosis is not rare, affecting over 2.5% of the population. This condition is often socially and professionally debilitating, leading to significant quality of life impairment. It most commonly involves the axillae, palms, soles, and face. Objective: To review hyperhidrosis and discuss and compare the treatment options currently available. Conclusions: Topical or systemic therapies may be helpful for patients with mild disease. Invasive surgical options, although often effective, are limited by complications. More recently, botulinum toxin injection has proven to be a safe and successful treatment for hyperhidrosis and results in high patient satisfaction. Botulinum toxin A (Botox, Allergan Inc., Irvine, CA) is currently approved in the United States, Canada, the United Kingdom, and many other countries for the treatment of axillary hyperhidrosis and is routinely used off-label for other anatomic sites.
ISSN:1203-4754
1615-7109
DOI:10.2310/7750.2007.00012