Interaction between vitamin D and parathyroid hormone on perinatal outcomes highlights significance of calcium metabolic stress in pregnancy

Clinical data and biological plausibility warrant exploration of a potential role for vitamin D in prevention of adverse perinatal outcomes, specifically hypertensive disorders of pregnancy. Stress to the calcium metabolic system, typified by elevated parathyroid hormone (PTH) levels, may arise from...

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Bibliographic Details
Published in:Proceedings of the Nutrition Society 2017, Vol.76 (OCE3), Article E48
Main Authors: Hemmingway, A., Kenny, L.C., Kiely, M.E.
Format: Article
Language:English
Subjects:
Calciferol
Calcium
Gestational age
Menopause
Metabolism
Nutrition
Parathyroid
Parathyroid hormone
Pregnancy
Small for gestational age
Vitamin D
Vitamin deficiency
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Summary:Clinical data and biological plausibility warrant exploration of a potential role for vitamin D in prevention of adverse perinatal outcomes, specifically hypertensive disorders of pregnancy. Stress to the calcium metabolic system, typified by elevated parathyroid hormone (PTH) levels, may arise from low calcium intake and/or low vitamin D status and has been associated with PE and small-for-gestational age (SGA) birth(5,6). [...]these results highlight the importance of considering vitamin D status within the broader calcium metabolic system in future explorations of nutrition and perinatal outcomes. 1.
ISSN:0029-6651
1475-2719
DOI:10.1017/S0029665117001203