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Epidermal growth factor inhibits Na-Pi cotransport in weaned and suckling rats

In the present study, we determined the effect of epidermal growth factor (EGF; 10 mug/100 g body wt) on sodium gradient-dependent phosphate transport (Na-Pi cotransport) regulation in suckling (12-day-old) and weaned (24-day-old) rats. Weaned rats had higher proximal tubular brush border membrane v...

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Published in:	American journal of physiology. Renal physiology 1999, Vol.45 (1), p.F72-F78
Main Authors:	ARAR, M, ZAJICEK, H. K, ELSHIHABI, I, LEVI, M, GONZALES, M, WILSON, P
Format:	Article
Language:	English
Subjects:	Biological and medical sciences Cell physiology Fundamental and applied biological sciences. Psychology Kidneys Membrane and intracellular transports Molecular and cellular biology Peptides Physical growth Proteins Rodents
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creator	ARAR, M ZAJICEK, H. K ELSHIHABI, I LEVI, M GONZALES, M WILSON, P
description	In the present study, we determined the effect of epidermal growth factor (EGF; 10 mug/100 g body wt) on sodium gradient-dependent phosphate transport (Na-Pi cotransport) regulation in suckling (12-day-old) and weaned (24-day-old) rats. Weaned rats had higher proximal tubular brush border membrane vesicle (BBMV) Na-Pi cotransport activity (232 +/- 16 in weaned vs. 130 +/- 9 pmol x 10s-1 x mg protein-1 in suckling rats, P < 0.05).
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source	American Physiological Society Journals
subjects	Biological and medical sciences Cell physiology Fundamental and applied biological sciences. Psychology Kidneys Membrane and intracellular transports Molecular and cellular biology Peptides Physical growth Proteins Rodents
title	Epidermal growth factor inhibits Na-Pi cotransport in weaned and suckling rats
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