Effect of Thyroid Replacement with Statin Therapy on Cognitive Functions and Lipid Profile in Hypothyroidism Patients

SH could be one of the causes of secondary hyperlipidaemia and should be viewed as an independent risk factor for atherosclerosis, along with obesity, hypertension, diabetes, etc.3 So in this study planned to compare the effect of Levothyroxine 50mcg with Atorvastatin 20 mg and Atorvastatin mono the...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences and research 2019-09, Vol.11 (9), p.3233-3236
Main Authors: Anandkumar, S, Shanmugapandiyan, P
Format: Article
Language:English
Subjects:
Anemia
Atherosclerosis
Cardiovascular disease
Cholesterol
Cognition & reasoning
Cognitive ability
Endocrinology
Enzymes
Hormones
Hospitals
Hypothyroidism
Lipids
Lipoproteins
Metabolism
Thyroid gland
Triglycerides
Womens health
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Summary:SH could be one of the causes of secondary hyperlipidaemia and should be viewed as an independent risk factor for atherosclerosis, along with obesity, hypertension, diabetes, etc.3 So in this study planned to compare the effect of Levothyroxine 50mcg with Atorvastatin 20 mg and Atorvastatin mono therapy in Cognitive skills and lipid profile. Data collection tool Data were collected through specially designed data entry format in order to collect the details of the Patient details including name, age, sex, known allergy, educational status, I.P no/O.P no, date of admission, date of discharge and patient history including present complaints, past medical history, past medication history, social history and family history, Vital signs (Body temperature, Blood pressure and pulse rate), lipid profile (Total cholesterol (TC), Triglycerides (TG), Low density lipoprotein (LDLC), High Density lipoprotein (HDL-C), Mini mental state examinations (MMSE), drugs treatment details were collected. [...]it shows that effective management of lipid profile was attain with the combination of levothyroxine and atrovastatin and also it proves that cardiovascular risk was reduced significantly on the proper management of thyroid replacement therapy as mention in the Table 4 & Figure 3. Martin S, Daya N, Lutsey P, Matsushita K, Fretz A, McEvoy J. Thyroid Function, Cardiovascular Risk Factors, and Incident Atherosclerotic Cardiovascular Disease: The Atherosclerosis Risk in Communities (ARIC) Study.
ISSN:0975-1459