Planimetric and Biomechanical Study of Local Effect of Pulegone on Full Thickness Wound Healing in Rat

Once the skin is injured, the normal collagen will be replaced by scar collagen and the connective tissue will not regain the original highly organised structure of collagen. [...]the healing skin is weaker and results in lower tensile strength as opposed to the normal skin (34). Conclusions The pul...

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Bibliographic Details
Published in:The Malaysian journal of medical sciences 2017-10, Vol.24 (5), p.52-61
Main Authors: Cheraghali, Zahra, Mohammadi, Rahim, Jalilzadeh-Amin, Ghader
Format: Article
Language:English
Subjects:
Antimicrobial agents
Biomechanics
Collagen
Diabetes
Growth factors
Laboratory animals
Oils & fats
Rodents
Surgery
Wound healing
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Summary:Once the skin is injured, the normal collagen will be replaced by scar collagen and the connective tissue will not regain the original highly organised structure of collagen. [...]the healing skin is weaker and results in lower tensile strength as opposed to the normal skin (34). Conclusions The pulegone resulted in significant improvement of full thickness wound healing. [...]from this study we concluded that pulegone had a reproducible wound healing potential in rats. GJ-A Statistical expertise: RM Obtaining of funding: ZC Administrative, technical, or logistic support: ZC Collection and assembly of data: ZC Correspondence Dr Rahim Mohammadi DVM (Islamic Azad University, Urmia Branch), DVSc (Urmia University) Assistant Professor of Veterinary Surgery Department Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Nazloo Road, Urmia, 57153 1177, Iran. Epidermal growth factor-containing wound closure enhances wound healing in non-diabetic and diabetic rats.
ISSN:1394-195X
2180-4303
DOI:10.2l3l5/mjms20l7.24.5.6