Apolipoprotein A-I gene expression is regulated by cellular zinc status in Hep G2 cells

The influence of Zn on the expression of the apolipoprotein A-I (apoA-I) gene in Hep G2 cells was examined. An depletion was achieved with a low-Zn (ZD) medium prepared from Zn-free growth medium (Opti), a ZD medium containing Chelex 100-extracted fetal bovine serum (CHE), and a medium containing ch...

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Bibliographic Details
Published in:American Journal of Physiology: Cell Physiology 1999-09, Vol.46 (3), p.C537-C544
Main Authors: WU, J. Y. J, YAN WU, REAVES, S. K, YI RAN WANG, LEI, P. P, LEI, K. Y
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cellular biology
Fundamental and applied biological sciences. Psychology
Genes
Liver. Bile. Biliary tracts
Proteins
Vertebrates: digestive system
Zinc
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Summary:The influence of Zn on the expression of the apolipoprotein A-I (apoA-I) gene in Hep G2 cells was examined. An depletion was achieved with a low-Zn (ZD) medium prepared from Zn-free growth medium (Opti), a ZD medium containing Chelex 100-extracted fetal bovine serum (CHE), and a medium containing chelator 1,10-phenathroline (OP).
ISSN:0363-6143
1522-1563