Regulation of Spi 2.1 and 2.2 gene expression after turpentine inflammation : discordant responses to IL-6

To examine the role of signal transducer and activation of transcription (STAT) proteins in the divergent regulation of these model genes after induction of APR, we evaluated the proximal promoters of the genes, focusing on STAT binding sites contained in these promoter elements.

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Bibliographic Details
Published in:American Journal of Physiology: Cell Physiology 1999-06, Vol.45 (6), p.C1374-C1382
Main Authors: BERRY, S. A, BERGAD, P. L, STOLZ, A. M, TOWLE, H. C, SCHWARZENBERG, S. J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cellular biology
Cytokines
Fundamental and applied biological sciences. Psychology
Genes
Inflammation
Liver
Molecular and cellular biology
Proteins
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Description
Summary:To examine the role of signal transducer and activation of transcription (STAT) proteins in the divergent regulation of these model genes after induction of APR, we evaluated the proximal promoters of the genes, focusing on STAT binding sites contained in these promoter elements.
ISSN:0363-6143
1522-1563