Swelling-activated cation-selective channels in A6 epithelia are permeable to large cations

Effects of basolateral monovalent cation replacements (Na+ by Li+, K+, Cs+, methylammonium, and guanidinium) on permeability to 86Rb of volume-sensitive cation channels (VSCC) in the basolateral membrane and on regulatory volume decrease (RVD), elicited by a hyposmotic shock, were studied in A6 epit...

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Bibliographic Details
Published in:American Journal of Physiology: Cell Physiology 1998-08, Vol.44 (2), p.C358-C366
Main Authors: JINQING LI, DE SMET, P, JANS, D, SIMAELS, J, VAN DRIESSCHE, W
Format: Article
Language:English
Subjects:
Biochemistry
Biological and medical sciences
Cell membranes. Ionic channels. Membrane pores
Cell structures and functions
Cells
Cellular biology
Fundamental and applied biological sciences. Psychology
Ions
Membranes
Molecular and cellular biology
Permeability
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Summary:Effects of basolateral monovalent cation replacements (Na+ by Li+, K+, Cs+, methylammonium, and guanidinium) on permeability to 86Rb of volume-sensitive cation channels (VSCC) in the basolateral membrane and on regulatory volume decrease (RVD), elicited by a hyposmotic shock, were studied in A6 epithelia in the absence of apical Na+ uptake.
ISSN:0363-6143
1522-1563