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P2Z/P2X7 receptor-dependent apoptosis of dendritic cells

Macrophages and thymocytes express P2Z/P2X7 nucleotide receptors that bind extracellular ATP. These receptor play a role in immune development and control of microbial infections, but their presence on dendritic cells has not been reported.

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Published in:	American Journal of Physiology: Cell Physiology 1999-05, Vol.45 (5), p.C1139-C1147
Main Authors:	COUTINHO-SILVA, R, PERSECHINI, P. M, DA CUNHA BISAGGIO, R, PERFETTINI, J.-L, TORRES DE SA NETO, A. C, KANELLOPOULOS, J. M, MOTTA-LY, I, DAUTRY-VARSAT, A, OJCIUS, D. M
Format:	Article
Language:	English
Subjects:	Anatomy & physiology Biological and medical sciences Cellular biology Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology Monocytes, macrophages Myeloid cells: ontogeny, maturation, markers, receptors Ribonucleic acid RNA
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container_start_page	C1139
container_title	American Journal of Physiology: Cell Physiology
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creator	COUTINHO-SILVA, R PERSECHINI, P. M DA CUNHA BISAGGIO, R PERFETTINI, J.-L TORRES DE SA NETO, A. C KANELLOPOULOS, J. M MOTTA-LY, I DAUTRY-VARSAT, A OJCIUS, D. M
description	Macrophages and thymocytes express P2Z/P2X7 nucleotide receptors that bind extracellular ATP. These receptor play a role in immune development and control of microbial infections, but their presence on dendritic cells has not been reported.
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source	American Physiological Society Free
subjects	Anatomy & physiology Biological and medical sciences Cellular biology Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology Monocytes, macrophages Myeloid cells: ontogeny, maturation, markers, receptors Ribonucleic acid RNA
title	P2Z/P2X7 receptor-dependent apoptosis of dendritic cells
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