Metabolic acidosis regulates rat renal Na-Si cotransport activity

Recently, we cloned a cDNA (NaSi-1) localized to rat renal proximal tubules and encoding the brush-border membrane (BBM) Na gradient-dependent inorganic sulfate (Si) transport protein (Na-Si cotransporter). The purpose of the present study was to determine the effect of metabolic acidosis (MA) on Na...

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Bibliographic Details
Published in:American Journal of Physiology: Cell Physiology 1999-06, Vol.45 (6), p.C1398-C1404
Main Authors: PUTTAPARTHI, K, MARKOVICH, D, HALAIHEL, N, WILSON, P, ZAJICEK, H. K, HUAMIN WANG, BIBER, J, MURER, H, ROGERS, T, LEVI, M
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cellular biology
Fundamental and applied biological sciences. Psychology
Kidneys
Membranes
Metabolism
Rodents
Vertebrates: urinary system
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Summary:Recently, we cloned a cDNA (NaSi-1) localized to rat renal proximal tubules and encoding the brush-border membrane (BBM) Na gradient-dependent inorganic sulfate (Si) transport protein (Na-Si cotransporter). The purpose of the present study was to determine the effect of metabolic acidosis (MA) on Na-Si cotransport activity and NaSi-1 protein and mRNA expression.
ISSN:0363-6143
1522-1563